The Lifespan Connectomics and Behavior Team (LCBT) is led by Dr. Xi-Nian Zuo, an applied mathematician and neuroscientist at the Institute of Psychology, Chinese Academy of Sciences (IPCAS) who specializes in neuroimaging methodology and developmental neuroscience. We have three research themes: 1) reliable neuroimaging measures (reliability and reproducibility), 2) human brain functional connectome and its development in health (normative functional connectomes) and 3) combination of the information from 1) and 2) to explore how specific aspects of psychological processes associate with brain function and mental/neurodegenerative diseases disrupt normal brain functioning (functional connectomics). Using modern neuroimaging techniques (mainly resting-state fMRI), we map the three levels of the intrinsic architecture within the brain connectome (i.e., region, subnetwork and entire functional connectome). We then direct our investigations to the brain development within different life spans, computational simulation on brain connectome and clinical psychology/psychiatry guided by our neuroimaging results. Our long-term goal is to address the complexity of human brain connectome in its function. We use integrative neuroimaging and computational modeling methods to explore psychology/disease-related patterns and complexities of functional connectome, seeking knowledge that will translate into a better life style and diagnosis/treatment for patients.